Benzalkonium Chloride (BKC)

Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants. It is also used as an antimicrobial preservative for pharmaceutical products. For most multi-dose aqueous nasal, ophthalmic and OTC products, Benzalkonium Chloride is the preservative of choice.

It has been used in eye drops as a preservative since the 1950s and it is still the most common preservative used in ophthalmic solutions at a concentration of 0.01 – 0.02%. It is an effective bactericidal and fungicidal agent that helps to minimize the growth of organisms in multi-dose containers.

CAS No. Chemical Structure Molecular Formula Strength
C22H40ClN 50.0% (±1%) w/w
pH Physical Appearance Density Packing
7.5 (±1) A white or yellowish-white powder or gelatinous, yellowish-white fragments 0.97(±0.01) g/ml 100 Kg HDPE carboys